When it comes to monetizing pharmacy websites, choosing the right ad network can significantly increase your Revenue Per Mille (RPM). The highest RPM ad networks for pharmacy sites typically offer niche targeting, high-demand healthcare-related ads, and compliance with medical content guidelines. Here are some of the top-performing options:

Mediavine

  • Best for: High-traffic, content-rich pharmacy blogs

  • Why it stands out: Offers premium RPM rates, especially for U.S.-based traffic, and provides excellent ad optimization tools.

  • Requirements: Minimum of 50,000 monthly sessions

AdThrive

  • Best for: Established pharmacy publishers

  • Why it stands out: High RPMs due to direct partnerships with healthcare and pharmaceutical brands.

  • Requirements: 100,000+ monthly pageviews and majority U.S. traffic

7Search PPC

  • Best for: Niche and mid-sized pharmacy sites

  • Why it stands out: Tailored PPC ad solutions for pharmaceutical and healthcare content, with competitive CPM and CPC rates.

  • Bonus: Supports custom ad placement and keyword-targeted traffic

Ezoic

  • Best for: Pharmacy blogs focused on SEO and long-form content

  • Why it stands out: AI-driven ad testing and layout optimization increase RPM over time.

  • Requirements: Flexible traffic requirements

PropellerAds

  • Best for: Diverse monetization (push ads, native, popunders)

  • Why it stands out: Allows monetization of less conventional pharmacy content with fairly high global RPMs.

  • Note: Not all formats are ideal for user experience

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